Rota/Adeno CombiStick One Step Test # R-5192
Rotaviruses are one of the major causes of pediatric gastroenteritis and diarrhea. Untreated, rotavirus infection may result in severe illness with dehydration and disturbances of the body's normal electrolyte balance, especially in babies and preschool children. Rotavirus is the cause of up to 50% of the hospitalized cases of diarrheal illness in infants and young children. Rotavirus induced dehydration is a major cause of infant morbidity in both developed and underdeveloped countries, and a major cause of infant mortality in the latter regions.
The highest prevalence of the disease is experienced in temperate climates during the cooler months of the year. In tropical climates rotavirus infection can occur year round. The age groups most susceptible to the disease are that of infants and children.
Adenoviruses have been implicated in a wide range of clinical diseases affecting mainly the respiratory, ocular and the gastrointestinal systems of the human. Some adenovirus serotypes are enteric and have emerged as a major source of pediatric gastroenteritis.
Diagnosis of rotavirus and adenovirus gastroenteritis is based on the identification of virus particles in the feces. These particles, shed in large numbers during infection, may be observed by electron microscopy (EM) or detected by immunological methods, such as the immunochromatographic method used in the Rota/Adeno CombiStick assay.
The One Step Rota/Adeno CombiStick (Cat. No. R-5192) is a rapid immunochromatographic test for use in the qualitative screening of human fecal samples for detection of the presence of rotavirus or adenovirus antigen.
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